A manifest of our clinical trials

The Study Hub showcases a collection of groundbreaking clinical trials — many of them world-firsts — powered by Spiral’s people and technology to deliver real-world impact and advance global health outcomes.

Primary Outcome: Day 90 mortality for pneumonia patients

Trial Outcome: determine the optimal intensive care treatment for patients after arrival in hospital

Trial Outcome: An adaptive platform design, running multiple domains concurrently to improve outcomes for pre-term babies

BLOG: STEPCARE

Learn more: A study engineered to explore the full human experience of cardiac arrest patients

“When something terrible happens to us, it doesn’t just happen to us. It happens to everyone around us. Sub-studies build on this broader view — from biological data collection in an ICU setting, to pain and mobility assessments at Day 30 and ongoing in-home care.”

  • ASCOT

    ASCOT: A clinical trial that will generate clinical evidence on treatment for COVID-19, which can be applied during a pandemic to reduce mortality.

  • CAPTIVATE

    CAPTIVATE: The Global Kidney Patient Trials Network (GKPTN) registry has enrolled 4334 patients with chronic kidney disease since May 2020 across 119 sites in 8 countries.

  • MEGA-ROX

    MEGA-ROX: Multicentre, multinational, randomised clinical trial to comapring conservative oxygen therapy with usual oxygen therapy in mechanically ventilated patients.

  • REDUSE

    REDUSE: Integrating research for human-centred treatment in septic shock.

  • SNAP

    SNAP: Aims to improve treatment outcomes for patients with Staphylococcus aureus bloodstream infections.

  • STEPCARE

    STEPCARE: Aims to determine the optimal intensive care treatment for patients after arrival in hospital.

  • STOP-KNEE-OA

    STOP-KNEE-OA: Subcutaneous Tirzepatide nce-weekly in Patients With Obesity and Knee Osteoarthritis

  • T1D PLUS

    T1D PLUS: This trial involves 40 sites across Europe, including the UK, Austria, France, Belgium, Germany, and Italy. 

  • TTM2

    TTM2: This trial is a phase III, multi-centre, randomised, parallel-group, clinical trial in resuscitated cardiac arrest patients admitted to the intensive care unit.

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