Infrastructure for complex clinical trials across every care setting

In Focus

Intensive Care


The most agile research platform in the world

Spiral designs trial infrastructure that manages complexity, supports clinical workflows, and protects data integrity: from ICU to community.

Randomisation is our superpower

We’re redefining the parameters of randomisation in all its forms.

The Study Hub showcases a collection of groundbreaking clinical trials - many of them world-firsts. They are powered by Spiral’s people and technology to deliver real-world impact and advance global health outcomes.

Primary Outcome: Day 90 mortality for pneumonia patients

Trial Outcome: determine the optimal intensive care treatment for patients after arrival in hospital.

Trial Update: An adaptive platform design, running multiple domains concurrently.

Thought leadership

Global Delivery Local Sovereignty

Global delivery, local sovereignty


Data residency isn’t a checkbox; it’s at the core of ethics, regulation, and community trust.

Engineered to explore the full human experience of cardiac arrest


This trial is not just collecting ICU data. It’s following people through their recovery and hearing from their ongoing caregivers as well.

Why checkboxes trip up clinical data

For research nurses, the way a question is built in the CRF can be the difference between a clean lock and a month of queries.


Human-centered design

  • Diane Mackle, Mega-Rox, MRINZ

    "This trial is about so much more than just numbers – it's about redefining what's possible in healthcare and making a lasting impact on patients' lives."

    Diane Mackle, Project Manager, MEGA-ROX Trial

  • Ly-Mee Yu, Panoramic Trial, University of Oxford

    “‘In clinical trials, especially academic clinical trials, we don’t often have the luxury of a full system that will do everything for us, normally there would be a separate system for separate things. Spiral provides this full system”.

    ~Ly-Mee Yu, Lead Statistician, PANORAMIC Trial

Global impact

Spiral's Global Impact and Success

International support that feels close to home

Based in New Zealand, we support trials globally.
We work closely with your team to design and deliver systems that respond to the realities of your study.

Globally recognised, trusted by the best

Receive Spiral Stories

Insights, trial updates, and design thinking from across ICU, wards, clinics, and community-based studies.