Infrastructure for complex clinical trials across every care setting

In Focus

Community-Based


The most agile research platform in the world

Spiral designs trial infrastructure that manages complexity, supports clinical workflows, and protects data integrity: from ICU to community.

The Study Hub showcases a collection of groundbreaking clinical trials - many of them world-firsts. They are powered by Spiral’s people and technology to deliver real-world impact and advance global health outcomes.

Primary Outcome: Day 90 mortality for pneumonia patients

Trial Outcome: determine the optimal intensive care treatment for patients after arrival in hospital.

Trial Update: An adaptive platform design, running multiple domains concurrently.

Randomisation is our superpower

We’re redefining the parameters of randomisation in all its forms.

Thought leadership

See you @ ANZCA


Proudly supporting ANZCA 2026. Building the culture, capability, and technology to support our clients and research peers well.

Why checkboxes trip up clinical data


For research nurses, the way a question is built in the CRF can be the difference between a clean lock and a month of queries.

Global Delivery Local Sovereignty

Global delivery, local sovereignty


Data residency isn’t a checkbox; it’s at the core of ethics, regulation, and community trust.

Meet the people behind complex clinical trials

Spiral brings together specialists who work alongside clinical research teams to deliver robust trial infrastructure across every care setting.

  • Diane Mackle, Mega-Rox, MRINZ

    "This trial is about so much more than just numbers – it's about redefining what's possible in healthcare and making a lasting impact on patients' lives."

    Diane Mackle, Project Manager, MEGA-ROX Trial

  • Ly-Mee Yu, Panoramic Trial, University of Oxford

    “‘In clinical trials, especially academic clinical trials, we don’t often have the luxury of a full system that will do everything for us, normally there would be a separate system for separate things. Spiral provides this full system”.

    ~Ly-Mee Yu, Lead Statistician, PANORAMIC Trial

Global impact

Spiral's Global Impact and Success

Globally recognised, trusted by the best

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Insights, trial updates, and design thinking from across ICU, wards, clinics, and community-based studies.